XKCD is a relatively well known and well loved webcomic in nerd circles. It's drawn and written by Randall Munroe. For the most part, the comic follows the antics of some very simple stick figures as they interact with technology and the modern world. Doesn't sound very funny but I highly recommend it.
Randal has a way of pointing out flaws in human perception and how we compartmentalize information. It's hard to explain without examples, so here are a couple.
Randall also comments extensively on the nature of science and some of its painful realities. I found the following comic to be an impressive discussion of what makes a good scientist in four panels and three colours.